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Endoplasmic reticulum (ER) stress and actors of unfolded protein response (UPR) have emerged as key hallmarks of hepatocarcinogenesis. Numerous reports have shown that the main actors in the UPR pathways are upregulated in HCC and contribute to the different facets of tumor initiation and disease progression. Furthermore, ER-stress inducers and inhibitors have shown success in preclinical HCC ...
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The safety life cy cle for m ining is an adaptation of the safety life cycle in Part 1 of IEC 61508 [IEC 1998a]. System safety activities include identifying hazards, a nalyzing the risks, designing to eliminate or reduce hazards, and using this approach over the entire system life cycle.
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How South Africa's Mining Industry Can Address Climate Change Challenges. To build an uncertainty advantage around climate change risk, mining executives should focus on three key priorities: developing a climate-conscious, scenario-based business strategy; climate-proofing their operations; and engaging stakeholders with an inspiring mission.
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A mining lifecycle consists of 5 stages (Newman et al. 2010), namely: prospecting, exploration, development, exploitation, and reclamation; and lasts for 10-30 years (King et al. 2017). Industry inputs are characterised by variable quality of deposits and their gradual depletion (Mudd 2007).
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Adaptation strategies to reduce smallholder farmers' vulnerability to climate variability and seasonality are needed given the frequency of extreme weather events predicted to increase during the next decades in sub-Saharan Africa, particularly in West Africa. We explored the linkages between selected agricultural adaptation strategies (crop diversity, soil and water conservation, trees on ...
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we adapt subgroup discovery to class association rule mining, and embed it into an adaptive approach for obtaining a rule set that aims to target a simple rule base with an adequate level of predictive power, i.e., combining simplicity and accura.cy 2. orf constructing the rule base, we utilize standard methods of rule selection and evaluation, .
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Opinion mining and sentiment analysis Bo Pang1 and Lillian Lee2 1 Yahoo! Research, 701 First Ave. Sunnyvale, CA 94089, U.S.A., bopang@yahoo-inc ... 4.4 Domain adaptation and topic-sentiment interaction 25 4.4.1 Domain considerations 25 4.4.2 Topic (and sub-topic or feature) considerations 26 ... (er) quality 49
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Jul 9, 2021The unfolded protein response (UPR) is a conserved cellular survival strategy which is activated in response to the accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER) lumen, an event known as ER-stress.
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5. COAL MINING METHODS Surface Mining Method Strip mining Slice mining Horizon mining Underground Mining Method Bord & Pillar Longwall Method Shortwall Method Advancing Retreating. 6. Surface MiningSurface Mining is used for about 40% of coal production in the world. Ore bodies close to the surface at depths less than approximately 180 ft (50 m ...
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1420 Austin Bluffs Parkway. Colorado Springs, CO 80918. Email rlewis5 [at]uccs.edu. D r. Lewis is the Program Director of the Masters of Computer Science. He is the recipient of numerous Outstanding Achievement: Teacher of the Year awards at the College of Engineering, Computer Science. He is the recipient of the Diversity & Inclusiveness Award ...
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Fennec foxes are opportunistic eaters. They forage for plants but also eat rodents, eggs, reptiles, and insects. Like most desert dwellers, the fennec fox has developed the ability to go for long ...
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Nov 10, 2020in addition to mining beyond the earth, advancing our understanding of microbe-mineral interactions in space could be applied to: (1) soil formation from nutrient-poor rocks 22, (2) formation of...
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pap er w esho ed that, in our domain, cluster mining outp er-formed traditional clustering algorithms. In this pap er w ein tro duce c onc eptual cluster mining: giv en a collection of ob jects, a pairwise similarit y mea-sure o v er those ob jects, and a conceptual language for describing them, w e searc h for a small set of cohesiv clusters ...
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Attempting to mix modern terrorist thrillers like "24" and "Die Hard" with sci-fi tropes didn't work quite as well as hoped. It wasn't exactly a faithful adaptation of Dick's story, but at just 96 ...
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Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M), encoded by the nuclear PCK2 gene, links TCA cycle intermediates and glycolytic pools through the conversion of mitochondrial oxaloacetate into phosphoenolpyruvate. In the liver PEPCK-M adjoins its profusely studied cytosolic isoform (PEPCK-C) potentiating gluconeogenesis and TCA flux. However, PEPCK-M is present in a variety of non ...
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hardrock mining industry is an important source of prosperity and value to Montana households, businesses and governments. Not just in the mining communities, but throughout the state. The state's eight largest hardrock mining, talc mining and cement materials facilities together with the ongoing exploration activities, ultimately
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A series of progressively more complex simulations are embedded in scaffolded activities and allow students to explore the connection between variations, adaptations, the interdependence of species, and the results of environmental pressure on populations over time.
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The solar modules are placed outside, sunlight gets absorbed by the solar cell material, and electricity is generated. 5. Solar energy is clean. And of course, solar power is a boon for a company's green footprint as well as its bottom line. A solar plant's energy payback time is less than two years.
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It is the natural process of wearing away topsoil, but human activities have accelerated the process. It is usually caused due to the removal of vegetation, or any activity that renders the ground dry. Farming, grazing, mining, construction and recreational activities are some of the causes of soil erosion. The effects of soil erosion are not ...
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It is a key step for knowledge base creation and text mining. Recent adaptation of deep learning methods for ER mitigates the need for dataset-specific feature engineering by constructing distributed representations of entity records.
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The NKCCCA aims to be such a bridge and provide a clearer analysis of the extent, consequences and damage that climate change can cause in Iceland and main adaptation measures that can be taken to reduce damage. - Passionate about my profession, the environment, healthy lifestyle, my family, CrossFit and weightlifting.
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Coal mining leaving large overburden which needs to be rehabilitated by conducting reclamation and re-vegetation. This study objective was to evaluate plant species composition after thirteen ...
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Mar 21, 2022In this report, we draw from this study by first outlining the private adaptation responses of the 37 largest global mining companies, and then by analysing extent to which climate risks have been...
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Reviewed here are recent studies which address the question as to whether genetic adaptation to high altitude has occurred. Common to these studies are the use of the oxygen transport system and the passage of time as organizing principles, and the recognition of the multifaceted ways in which genetic factors can influence physiological processes.
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3. Introduction Text Mining is a Discovery Text Mining is also referred as Text Data Mining (TDM) and Knowledge Discovery in Textual Database (KDT). Text Mining is used to extract relevant information or knowledge or pattern from different sources that are in unstructured or semi-structured form.
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This is known as domain adaptation (DA), which has achieved great successes in computer vision and natural language processing, but is not systematically studied for ER. Our goal is to systematically explore the benefits and limitations of a wide range of DA methods for ER.
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Abstract. In 2014, South African playwright Brett Bailey and Belgian composer Fabrizio Cassol gave the world a contemporary operatic version of Macbeth set in the eastern provinces of the Democratic Republic of Congo (DRC). We cannot simply call it an adaptation; rather, it is an adaptation based on a (fictional) performance of Verdi's adaptation of Shakespeare's Macbeth.
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Three different recovery phases including early restoration (ER), middle restoration (MR), and later restoration (LR) were selected as our experimental sites in August 2019, according to the dominant vegetation types (herb, shrub, and tree) in the natural restoration area of Sb mining. The characteristics of each stage were presented in Table 1.
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Edinger, E. 2012. Gold mining and submarine tailings disposal: Review and case study. Oceanography 25(2):184 ... sharing, adaptation, distribution, and reproduction in any medium or format as long as users cite the materials appropriately, provide a link to the Creative Commons license, and indicate the changes that were made to the original ...
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tive, e.g. video encoding, stream mining etc. These applications are capable of operating in various con g-urations by adapting to certain input or environmen-tal conditions in turn producing similar or di erent quality of service. This notion can be extended to let variation-a ected hardware drive application adapta-tion. 2.
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Fuzzy mining—Adaptive process simplification based on multi-perspective metrics. In International Conference on Business Process Management. G. Alonso, P. Dadam, and M. Rosemann (Eds.), Vol. 4714, Springer, Berlin, 328-343. Marwan Hassani. 2019. Concept drift detection of event streams using an adaptive window.
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by introducing a difficult sample mining strategy in the training phase, perform target detection on difficult samples (no targets) in the first training process, and collect all detected rectangular frames, then use the samples misclassified by the model to expand the difficult sample set, and finally add the difficult sample set to the training .
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Research Intelligence. Insights via analytics for improved research strategy and impact. Clinical Decision Support. Improve outcomes for patients. Healthcare Education. Smart Learning solutions for faculty and students. R&D Workflow Support. Discipline-specific tools for your science, pharma, and engineering teams. Research platforms.
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This article presents the adoption of ICT innovation as part of the adaptation strategies towards reducing the mining sector's vulnerability and exposure to climate change disaster risks. Document analysis and systematic literature review were adopted as the methodology.
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4 days agoIt is a key step for knowledge base creation and text mining. Recent adaptation of deep learning methods for ER mitigates the need for dataset-specific feature engineering by constructing distributed representations of entity records.
WhatsApp:+8617329420102
er a preset course for days to map a broad swath of seabed, or can be used to ... capabilities available for mining but significant adaptations will be required to Wi conform to the more selective extraction processes required for hard min-eral deposits. This will surely happen, however. th t
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Using bacteria to dissolve minerals, releasing the metals locked inside, is called bioleaching. Palin's developing something different: a biological mining (not melting) process. Because seawater metals are already dissolved, his bacteria simply collect them. "A mining industry that's in balance with nature," he says.
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Background Early prediction of hospital mortality is crucial for ICU patients with sepsis. This study aimed to develop a novel blending machine learning (ML) model for hospital mortality prediction in ICU patients with sepsis. Methods Two ICU databases were employed: eICU Collaborative Research Database (eICU-CRD) and Medical Information Mart for Intensive Care III (MIMIC-III). All adult ...
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were derived from the same process model, but slightly di er in structure. Generally, such model variants are expensive to configure and maintain. This paper introduces two di erent scenarios for learning from process model adaptations and for discovering a reference model out of which the variants can be configured with minimum e orts.
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Based on the novel by Daniel Woodrell and released in 2010, it is the story of a teenage named Ree (Jennifer Lawrence, before her rise to fame and giving the best performance of her career) who lives in the Ozark Mountains with her mother and younger siblings.
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